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Bioassays, kits, and reagents used to analyze various properties of living cell samples. Products include apoptosis assays, signal transduction assays, and cell growth and differentiation assays.
Cayman's Early Apoptosis Detection Assay Kit employs FITC-conjugated annexin V as a probe for phosphatidylserine (PS) on the outer membrane of apoptotic cells, TMRE as a probe for ΔΨm, DAPI as an indicator of membrane permeability/cell viability, and TO-PRO-3 to indicate the selective permeability of pannexin channels. The Early Apoptosis Detection Assay Kit allows phenotypic characterization of multiple different cell death parameters at the single-cell level.
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JNJ-26854165 (Serdemetan) acts as a HDM2 ubiquitin ligase antagonist and also induces early apoptosis in p53 wild-type cells, inhibits cellular proliferation followed by delayed apoptosis in the absence of functional p53. Phase 1. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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The R-PLEX Human Annexin A1 Assay from Meso Scale Diagnostics is a multiplex immunoassay kit that allows for the quantitative measurement of Annexin A1 in human serum plasma and cell culture supernatants It utilizes electrochemiluminescence (ECL) detection technology and provides high sensitivity broad dynamic range and intra- and inter-assay precision This assay requires an MSD instrument and provides components for one 96-well plate including coated plates calibrators controls diluent and detection antibodies It can detect Annexin A1 concentrations between 0 04 - 1500 ng/mL with an approximate 3 5 hour total assay time
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